New gut bacteria that help in reversing diabetes and obesity.


There is a new butyrate producing bacteria that plays a powerful role in our health. They determine our ability to prevent and reverse diabetes, improve insulin sensitivity and assist in fighting cancer.


It’s called Akkermansia muciniphila. It was discovered 14 years ago,  and healthy levels range from between 1% -  5% of all intestinal bacteria in adults. It plays a critical  role in preserving the protective mucus layer that lines the walls of our intestines. It also plays a significant role in ensuring  that the polyphenols we eat in plant-based foods are bio-available to our cells. So how effective our bodies are in harvesting the benefits from the veggies and fruits is partly determined by the abundance of this species in out gut.


You can find  the level of Akkermansia  muciniphila  in your gut by reviewing the Probiotic Section of your 3TandAi Personalized Nutrition and Performance report.

Your personalized nutrition plan will discuss ways  to nurture their growth in your gut, and as we tend to lose them with age, ways to maintain — and even restore — as we age.

Insulin resistance is the gradual decline of the body’s ability to efficiently metabolize carbs and sugar and use food and burn stored fat for fuel leading to prediabetes and type 2 diabetes.

Insulin resistance is also linked to a range of chronic ills, from obesity, gout, PCOS, Alzheimer's, erectile dysfunction, inflammation to reduced  immunity as we grow old.

Published this week in the journal Science Translational Medicine, the new research found that taking steps to boost A. muciniphila in the gut reduced  insulin resistance.

A  2018 study of cancer patients suggests that it plays a role in immune response. Patients with a greater abundance of Akkermansia in their guts responded significantly better to a new generation of immunotherapy.  When researchers took the stool of a patient who responded positively to the cancer-fighting therapy and transplanted it into lab animals with human cancers, the recipient animals became more likely to respond positively to the same treatment.

So what should I do?

Currently, there is no commercially available probiotic supplement that contains Akkermansia muciniphila.  The most effective way to increase Akkermansia muciniphila is through consuming foods rich in prebiotics that promote preferential growth of this helpful species - Its like providing the right "fertilizer"for your gut.

Akkermansia can be increased by consuming polyphenol-rich foods, including:

  • Pomegranate (attributed to ellagitannins and their metabolites) 14
  • Grape polyphenols (grape seed extract) (proanthocyanidin-rich extracts may increase mucus secretion, therefore creating a favorable environment for Akkermansia to thrive)  15  16
  • Cranberries  17

Increasing Akkermansia colonization of the colon can be promoted by the administration of prebiotic substrates, including:

  • arabinoxylan  11
  • inulin  12

Stay Informed. Stay Healthy!

Author: Priyaranjan Sinha


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