Peer-reviewed actuarial claims analysis confirms up to 9X ROI, demonstrating the power of gut microbiome and genetics-based care.

MOUNTAIN VIEW, Calif. — December 19, 2025— Digbi Health, the pioneer of Precision Biology–based chronic care, today announced actuarially validated healthcare cost savings for employers, supported by a newly published, multi-year medical claims analysis in the peer-reviewed journal Healthcare.

The analysis confirms that employers using Digbi Health’s Precision Biology platform achieved actuarially guaranteed, hard-dollar reductions in medical claims, driven by lower pharmaceutical utilization and reduced inpatient and outpatient costs. These savings were achieved by treating five chronic conditions — obesity, metabolic, gastrointestinal, mental health, and auto-immune — on a single platform, informed by genetic insights, gut microbiome analysis, and more than 8,000 biomarkers.

This announcement marks a critical milestone for digital health, an industry that has historically relied on “soft” and “vibe” ROI metrics such as engagement, while struggling to demonstrate direct medical cost reduction.

Validated Cost Savings by Condition

The peer-reviewed claims analysis evaluated multiple years of medical spend across seven U.S. self-insured employers, comparing Digbi Health participants with matched non-participants. The study identified significant reductions in medical claims, including:

• Digestive and GI cost reduction: - $9,240+ per member per year 

• Obesity-related medical cost reduction: -  $4,884+ per member per year

• Anxiety-related medical cost reduction : - $1,356+ per member per year 

• Overall medical spend Reduction: -$3,012 per member per year 

Precision Biology as the New Standard of Care

While most high-cost claimants are polychronic, traditional digital care programs treat these conditions in silos, resulting in fragmented care, poor engagement, overlapping medications, and escalating costs.

Digbi Health's Precision Biology platform targets the root cause of biological and behavioral changes by analyzing biomarkers from the gut microbiome, blood, and genetic tests, along with dietary intake, to treat multiple conditions simultaneously — replacing fragmented point solutions with a single, coordinated system of care.

"More than 100 employers are already using Digbi Health to manage 70% of their healthcare controllable costs driven by GLP-1s, obesity, metabolic, and GI conditions. Precision Biology is no longer the future of care — it is the new standard,” said Ranjan Sinha, Founder and CEO of Digbi Health.
“Just as we pioneered Precision Biology in chronic care, we are now showing leadership in proving that root-cause treatment can materially reduce medical claims across multiple conditions and clean up the point solutions proliferation.”

Extending Savings in the GLP Era

Digbi Health continues to expand its GLP-1 offering to include direct-to-employer and employee cash pay fulfillment options, while supporting PBM and 340B medication access.

By combining GLP-1 therapy with biologically personalized support, Digbi Health achieves significant reductions in GLP-1 adverse effects, thereby improving adherence and weight loss outcomes, and further extending the medical savings demonstrated in the claims analysis.

About Digbi Health

Our mission is to end the scourge of food-related chronic illness - obesity, metabolic, digestive, autoimmune, and mental health - for this and future generations to advance human longevity. Digbi combines thousands of genetics, gut microbiome, CGM, blood biomarkers, and AI-powered insights to deliver personalized, nutrition-first care solutions to prevent and treat obesity, metabolic, and gastrointestinal issues in 40 languages.

Digbi is committed to making personalized care universally accessible to individuals through their employers, insurance-covered plans, and Medicare, creating personalized, proactive, predictive, data-driven, and home-based care that turns food from a cause of illness into a means of medicine. 

With over 100 employers offering Digbi Health, Precision Biology isn't the future of care. It's the New Standard.